Christine Fox, MD, MAS

Associate Professor
Director, Pediatric Stroke and Cerebrovascular Disease Center
Principal Investigator of Project 3, UCSF Center of Excellence in Hemorrhagic Stroke Research
Principal Investigator of Seizures and Children’s Outcomes after Stroke (SCOUTS) Study
Neurology
[email protected]
Publications: 

Risk factors associated with in-hospital complications for pediatric sickle-cell disease-associated moyamoya syndrome: a nationwide cross-sectional study.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Osorio RC, Raygor KP, Rinaldo L, Fox CK, Bhasin N, Abla AA, Gupta N

Abstract 112: Assessing the Impact of the COVID-19 Pandemic on Childhood Arterial Ischemic Stroke: An Unanticipated Natural Experiment.

Stroke

Heather J Fullerton, Clara Di Germanio, Nancy K Hills, Lauren A Beslow, Dana D Cummings, Nomazulu Dlamini, Christine K Fox, Lisa R Sun, Philip Norris

Abstract TMP2: Longitudinal Risk of Seizures in Patients With Brain Arteriovenous Malformations.

Stroke

Samyami S Chowdhury, Jeffrey Nelson, Shantel Weinsheimer, Jonas Schollenberger, Heather J Fullerton, Christine K Fox, Helen Kim

Abstract TMP60: Contralesional Brain Regions Mirror the Volume Changes of Their Homologous Counterparts in the Ipsilesional Hemisphere in Children During the First Year After Unilateral Intracerebral Hemorrhage.

Stroke

Hannah L Choi, Shivani Mahuvakar, Lanya T Cai, Helen Kim, David A Saloner, Christine K Fox, Jarod Roland, Heather J Fullerton, Pratik Mukherjee

Abstract TP6: Identification of Circulating Epigenetic Biomarkers for Seizure in Brain Arteriovenous Malformation by Methylome Profiling.

Stroke

Peter Park, Jeffrey Nelson, Christine K Fox, Adam Numis, Nerissa Ko, Ethan Winkler, Charles McCulloch, Helen Kim, Shantel Weinsheimer

Abstract WP217: 4D Flow MRI Monitoring of Pediatric Brain Arteriovenous Malformations: A Feasibility Study.

Stroke

Jonas Schollenberger, Shivani Mahuvakar, Christine K Fox, Pratik Mukherjee, Heather J Fullerton, Helen Kim, David Saloner

Multicenter Study of Long-term Outcomes and Quality of Life in PHACE Syndrome after Age 10.

The Journal of pediatrics

Braun M, Frieden IJ, Siegel DH, George E, Hess CP, Fox CK, Chamlin SL, Drolet BA, Metry D, Pope E, Powell J, Holland K, Ulschmid C, Liang MG, Barry KK, Ho T, Cotter C, Baselga E, Bosquez D, Jain SN, Bui JK, Lara-Corrales I, Funk T, Small A, Baghoomian W, Yan AC, Treat JR, Hogrogian GS, Huang C, Haggstrom A, List M, McCuaig CC, Barrio V, Mancini AJ, Lawley LP, Grunnet-Satcher K, Horii KA, Newell B, Nopper A, Garzon MC, Scollan ME, Mathes EF

A quantitative EEG index for the recognition of arterial ischemic stroke in children.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

Caffarelli M, Karukonda V, Aghaeeaval M, McQuillen PS, Numis AL, Mackay MT, Press CA, Wintermark M, Fox CK, Amorim E, SIPS Investigators (see Appendix)

350 A Comparison of Incidental and Symptomatic Unruptured Brain Arteriovenous Malformations in Children.

Neurosurgery

Alex Y. Lu, Ethan A. Winkler, Joseph Garcia, Kunal P. Raygor, Heather Fullerton, Christine Fox, Helen Kim, Kurtis Ian Auguste, Peter P. Sun, Steven Hetts, Michael T. Lawton, Adib Adnan Abla, Nalin Gupta

A comparison of incidental and symptomatic unruptured brain arteriovenous malformations in children.

Journal of neurosurgery. Pediatrics

Lu AY, Winkler EA, Garcia JH, Raygor KP, Fullerton HJ, Fox CK, Kim H, Auguste KI, Sun PP, Hetts SW, Lawton MT, Abla AA, Gupta N

Abstract 52: Prevalence Of Somatic Activating Kras Mutations In Pediatric And Adult Sporadic Brain Arteriovenous Malformations.

Stroke

Ethan A Winkler, Joseph Garcia, Cynthia Tsang, Jeffrey Nelson, Charles McCulloch, Shantel Weinsheimer, Christine K Fox, Heather Fullerton, Nerissa Ko, Hua Su, Tomasz Nowakowski, Daniel L Cooke, Steven Hetts, Ekin Guney, MELIKE PEKMEZCI, Tarik Tihan, Michael Lawton, Adib Abla, Nalin Gupta, Helen Kim

Abstract TP157: Interleukin Plasma Levels And Risk Of Hemorrhage In Pediatric Brain Arteriovenous Malformation Patients.

Stroke

Shweta A Chawla, Shantel Weinsheimer, Jeffrey Nelson, Charles McCulloch, Adib Abla, Nalin Gupta, Daniel L Cooke, Steven Hetts, David Saloner, Yi Li, Christine K Fox, Heather J Fullerton, Helen Kim

Hemorrhagic Stroke in Children and Adults With Sickle Cell Anemia: The Post-STOP Cohort.

Stroke

Fox CK, Leykina L, Hills NK, Kwiatkowski JL, Kanter J, Strouse JJ, Voeks JH, Fullerton HJ, Adams RJ, Post-STOP Study Group

Socioeconomic factors associated with pediatric moyamoya disease hospitalizations: a nationwide cross-sectional study.

Journal of neurosurgery. Pediatrics

Raygor KP, Phelps RRL, Rutledge C, Raper DMS, Molinaro A, Fox CK, Gupta N, Abla AA

Validation of the Ruptured Arteriovenous Malformation Grading Scale in a pediatric cohort.

Journal of neurosurgery. Pediatrics

Garcia JH, Rutledge C, Winkler EA, Carrete L, Morshed RA, Lu AY, Saggi S, Fox CK, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Lawton MT, Gupta N, Abla AA

Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of Excellence.

Stroke

Sheth KN, Anderson CD, Biffi A, Dlamini N, Falcone GJ, Fox CK, Fullerton HJ, Greenberg SM, Hemphill JC, Kim A, Kim H, Ko NU, Roland JL, Sansing LH, van Veluw SJ, Rosand J

Factors associated with seizures at initial presentation in pediatric patients with cerebral arteriovenous malformations.

Journal of neurosurgery. Pediatrics

Garcia JH, Winkler EA, Morshed RA, Lu A, Ammanuel SG, Saggi S, Wang EJ, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Lawton MT, Abla AA, Gupta N

Seizure Incidence Rates in Children and Adults With Familial Cerebral Cavernous Malformations.

Neurology

Fox CK, Nelson J, McCulloch CE, Weinsheimer S, Pawlikowska L, Hart B, Mabray M, Zafar A, Morrison L, Zabramski JM, Akers A, Kim H

Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation.

Molecular genetics & genomic medicine

Choksi F, Weinsheimer S, Nelson J, Pawlikowska L, Fox CK, Zafar A, Mabray MC, Zabramski J, Akers A, Hart BL, Morrison L, McCulloch CE, Kim H

Pediatric moyamoya MRI score: an imaging-based scale to predict outcomes in surgically treated pediatric patients with moyamoya.

Neurosurgical focus

Garcia JH, Morshed RA, Winkler EA, Li Y, Fox CK, Fullerton HJ, Rutledge C, Beniwal AS, Lawton MT, Abla AA, Gupta N, Hetts SW

Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature.

Pediatric neurosurgery

Yue JK, Chang D, Oh T, Winkler EA, Lu AY, Hetts SW, Young EP, Reddy AT, Fox CK, Abla AA, Roland JL

Pediatric Ischemic Stroke: An Infrequent Complication of SARS-CoV-2.

Annals of neurology

Beslow LA, Linds AB, Fox CK, Kossorotoff M, Zuñiga Zambrano YC, Hernández-Chávez M, Hassanein SMA, Byrne S, Lim M, Maduaka N, Zafeiriou D, Dowling MM, Felling RJ, Rafay MF, Lehman LL, Noetzel MJ, Bernard TJ, Dlamini N

Asymptomatic rotational vertebral artery compression in a child due to head positioning for cranial surgery: illustrative case.

Journal of neurosurgery. Case lessons

Caton MT, Narsinh K, Baker A, Abla AA, Roland JL, Halbach VV, Fox CK, Fullerton HJ, Hetts SW

Clinical outcomes after revascularization for pediatric moyamoya disease and syndrome: A single-center series.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Morshed RA, Abla AA, Murph D, Dao JM, Winkler EA, Burkhardt JK, Colao K, Hetts SW, Fullerton HJ, Lawton MT, Gupta N, Fox CK

Single center series of boys with recurrent strokes and rotational vertebral arteriopathy.

Neurology

Fox CK, Fullerton HJ, Hetts SW, Halbach VV, Auguste KI, Lawton MT, Gupta N

Bringing high-grade arteriovenous malformations under control: clinical outcomes following multimodality treatment in children.

Journal of neurosurgery. Pediatrics

Winkler EA, Lu A, Morshed RA, Yue JK, Rutledge WC, Burkhardt JK, Patel AB, Ammanuel SG, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke D, Hetts SW, Lawton MT, Abla AA, Gupta N

Validation of the pediatric stroke outcome measure for classifying overall neurological deficit.

Pediatric research

Slim M, Fox CK, Friefeld S, Dlamini N, Westmacott R, Moharir M, MacGregor D, deVeber G

Abstract 89: Incidence and Characteristics of Hemorrhagic Stroke Among Post-STOP Participants.

Stroke

Liza A Leykina, Christine K Fox, Nancy K Hills, Julie Kanter, Janet L Kwiatkowski, Ariana Tinker, Jenifer H Voeks, Heather J Fullerton, Robert J Adams

Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study.

Neurology

Goeggel Simonetti B, Rafay MF, Chung M, Lo WD, Beslow LA, Billinghurst LL, Fox CK, Pagnamenta A, Steinlin M, Mackay MT

Clinical and Imaging Outcomes After Combined Direct and Indirect Bypass for Pediatric Moyamoya Disease: A Single Center Retrospective Series.

Neurosurgery

Ramin A Morshed, Daniel Murph, Jasmin Dao, Kathleen Colao, Lauro Avalos, Steven Hetts, Adib A Abla, Christine Fox, Michael T Lawton, Nalin Gupta

Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children.

Pediatric neurology

Chung MG, Guilliams KP, Wilson JL, Beslow LA, Dowling MM, Friedman NR, Hassanein SMA, Ichord R, Jordan LC, Mackay MT, Rafay MF, Rivkin M, Torres M, Zafeiriou D, deVeber G, Fox CK

Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management.

Stroke

Guilliams KP, Kirkham FJ, Holzhauer S, Pavlakis S, Philbrook B, Amlie-Lefond C, Noetzel MJ, Dlamini N, Sharma M, Carpenter JL, Fox CK, Torres M, Ichord RN, Jordan LC, Dowling MM

Socioeconomic determinants of outcome after childhood arterial ischemic stroke.

Neurology

Jordan LC, Hills NK, Fox CK, Ichord RN, Pergami P, deVeber GA, Fullerton HJ, Lo W

Children with post-stroke epilepsy have poorer outcomes one year after stroke.

International journal of stroke : official journal of the International Stroke Society

Fox CK, Jordan LC, Beslow LA, Armstrong J, Mackay MT, deVeber G

Population-based study of ischemic stroke risk after trauma in children and young adults.

Neurology

Fox CK, Hills NK, Vinson DR, Numis AL, Dicker RA, Sidney S, Fullerton HJ

Abstract WMP111: Socioeconomic Determinants of Outcome After Childhood Arterial Ischemic Stroke.

Stroke

Lori C Jordan, Nancy K Hills, Warren Lo, Rebecca N Ichord, Christine K Fox, Paola Pergami, Jorina Elbers, Gabrielle A deVeber, Heather J Fullerton

Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence.

Stroke

Fullerton HJ, deVeber GA, Hills NK, Dowling MM, Fox CK, Mackay MT, Kirton A, Yager JY, Bernard TJ, Hod EA, Wintermark M, Elkind MS

Prolonged or recurrent acute seizures after pediatric arterial ischemic stroke are associated with increasing epilepsy risk.

Developmental medicine and child neurology

Fox CK, Mackay MT, Dowling MM, Pergami P, Titomanlio L, Deveber G

Neonatal seizures triple the risk of a remote seizure after perinatal ischemic stroke.

Neurology

Fox CK, Glass HC, Sidney S, Smith SE, Fullerton HJ

Abstract WP201: Ischemic Stroke Risk After Traumatic Head or Neck Injury.

Stroke

Christine K Fox, Nancy K Hills, Stephen Sidney, David R Vinson, Heather J Fullerton

Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium.

Pediatric neurology

Sinclair AJ, Fox CK, Ichord RN, Almond CS, Bernard TJ, Beslow LA, Chan AK, Cheung M, deVeber G, Dowling MM, Friedman N, Giglia TM, Guilliams KP, Humpl T, Licht DJ, Mackay MT, Jordan LC

Abstract T MP66: Injury to the Head or Neck Increases Risk of Ischemic Stroke Three-fold After Trauma.

Stroke

Christine K Fox, Adam L Numis, Steve Sidney, Heather J Fullerton

Arterial ischemic stroke in children: risk factors and etiologies.

Current neurology and neuroscience reports

Numis AL, Fox CK

Acute seizures predict epilepsy after childhood stroke.

Annals of neurology

Fox CK, Glass HC, Sidney S, Lowenstein DH, Fullerton HJ

Abstract 77: Posterior Circulation Stroke in Children Due to Cervical Spine Abnormalities.

Stroke

Christine K Fox, Charles E Stout, Nalin Gupta, Michael T Lawton, Christopher F Dowd, Heather J Fullerton

Abstract 41: Acute Seizures and Neurologic Deficits Predict Epilepsy After Pediatric Stroke.

Stroke

Christine K Fox, Hannah C Glass, S. Claiborne Johnston, Stephen Sidney, Mai N Nguyen-Huynh, Heather J Fullerton

Recent advances in childhood arterial ischemic stroke.

Current atherosclerosis reports

Fox CK, Fullerton HJ

Minocycline confers early but transient protection in the immature brain following focal cerebral ischemia-reperfusion.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Fox C, Dingman A, Derugin N, Wendland MF, Manabat C, Ji S, Ferriero DM, Vexler ZS

Infant botulism, type F, presenting at 54 hours of life.

Pediatric neurology

Keet CA, Fox CK, Margeta M, Marco E, Shane AL, Dearmond SJ, Strober JB, Miller SP

Recent advances in infant botulism.

Pediatric neurology

Fox CK, Keet CA, Strober JB

Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model.

Neurobiology of disease

Mu D, Jiang X, Sheldon RA, Fox CK, Hamrick SE, Vexler ZS, Ferriero DM

Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain.

Stroke

Manabat C, Han BH, Wendland M, Derugin N, Fox CK, Choi J, Holtzman DM, Ferriero DM, Vexler ZS

Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis.

Liver

Fox CK, Furtwaengler A, Nepomuceno RR, Martinez OM, Krams SM

CD8+ cells are not necessary for allograft rejection or the induction of apoptosis in an experimental model of small intestinal transplantation.

Journal of immunology (Baltimore, Md. : 1950)

Krams SM, Hayashi M, Fox CK, Villanueva JC, Whitmer KJ, Burns W, Esquivel CO, Martinez OM

Human hepatocytes produce an isoform of FAS that inhibits apoptosis.

Transplantation

Krams SM, Fox CK, Beatty PR, Cao S, Villanueva JC, Esquivel CO, Martinez OM